Sara Andres, PhD
Assistant Professor, Department of Biochemistry and Biomedical Sciences
(905) 525-9140 x 21063
Health Sciences Centre (HSC) 4H38
Antimicrobial resistance arises through multiple mechanisms, one of which is the ability of bacteria to survive DNA damage. The Andres lab is interested in understanding the fundamental molecular mechanisms behind bacterial DNA damage response and repair pathways that contribute to microbial survival. They utilize a combination of structural biology, biochemistry, and cell biology to determine the unique and critical protein and nucleic acid components in these pathways that can be targeted for new therapeutic strategies aimed at drug-resistant infections.
Structural–Functional Studies of Burkholderia cenocepacia d-Glycero-β-d-manno-heptose 7-Phosphate Kinase (HldA) and Characterization of Inhibitors with Antibiotic Adjuvant and Antivirulence Properties (2013)