Russell Bishop, PhD

Associate Professor, Department of Biochemistry and Biomedical Sciences

bishopr@mcmaster.ca

(905) 525-9140 x 28810

Health Sciences Centre (HSC) 4H31B

McMaster University

The Bishop Lab Website

Research Interests

PagP is an outer membrane enzyme of Gram-negative bacteria that functions to modulate the host immune response to infections. PagP not only fortifies the outer membrane permeability barrier to provide enhanced antimicrobial resistance, but it can also function as a phospholipid-recycling sensory transducer. The co-evolution of eukaryotic hosts with bacteria has revealed multiple roles for PagP to guide the development of vaccine adjuvants and novel strategies to treat infections.

2019 The David Braley Centre for Antibiotic Discovery at McMaster University