Lori Burrows, PhD
Professor, Department of Biochemistry and Biomedical Sciences
The Burrows lab studies how bacteria interact with surfaces using common grappling hook-like virulence factors called type IV pili, which are potential drug and vaccine targets. Surface interactions and/or exposure to subinhibitory concentrations of antibiotics lead to the formation of antimicrobial tolerant biofilms. By understanding the pathways that lead to biofilm development, we can both inhibit and exploit them to identify new antimicrobials.
Structural–Functional Studies of Burkholderia cenocepacia d-Glycero-β-d-manno-heptose 7-Phosphate Kinase (HldA) and Characterization of Inhibitors with Antibiotic Adjuvant and Antivirulence Properties (2013)