UNDERSTANDING ANTIMICROBIAL RESISTANCE
What Are Antimicrobials?
Antimicrobials are powerful medicines that are used to treat and prevent infections caused by dangerous microorganisms. They do this by either killing the agent or halting their growth. Antimicrobials cure life-threatening diseases and enable major surgeries, organ and stem cell transplants, and cancer chemotherapies to save millions of lives each year. Antimicrobials that are specifically used against bacteria are called antibiotics.
What is Antimicrobial Resistance (AMR)?
When the microorganisms that cause infection are no longer sensitive to the drugs designed to eliminate them, they are considered "drug-resistant". Drug-resistant infections are difficult and expensive to treat and are often life-threatening.
How Serious is AMR?
Public health agencies around the world consider AMR to be “one of the biggest threats to global health, food security, and development today” (The World Health Organization, 2017). Currently, infections resulting from antimicrobial resistance are estimated to kill approximately 700,000 people globally each year.
If no action is taken, this number is expected to rise to a staggering 10 million people by 2050, and cost our global economy $100 trillion US dollars.
How Do We Solve This Problem?
Solutions to the global AMR crisis include the discovery and development of:
New ways to block resistance or enhance antibiotic activity
Vaccines to prevent disease
New diagnostics to identify superbugs
Careful AMR management strategies.
The David Braley Centre for Antibiotic Discovery and it's dedicated partners aim to address the global challenge of AMR through all of these strategies.
Successfully tackling the AMR challenge requires dedicated support from key players across a multitude of sectors. Our partners are committed to helping translate innovative ideas into meaningful solutions.